EFFECT OF SUBLINGUAL NITROGLYCERINE ON PAIN RELIEF IN RENAL AND URETERAL COLIC

The effect of sublingual nitroglycerine (TNG) on relieving pain in renal and ureteral colic was studied in a randomized, prospective, double blind and placebo controlled clinical trial. One hundred out-patients between 16-60 years of age from either sex who were admitted to the urology emergency center of Ayatollah Taleghani and Ashrafi Esfahani hospitals were chosen for this study. They were divided into two groups fifty-one of them were treated with TNG (0.4 mg initially and two similar doses if necessary at 5 minute intervals) and the remaining received placebo. The scoring of pain was performed using Lee et aI's method. Chi-square test was used for statistical analysis of data. Although the severity of pain was reduced one degree by TNG (p<0.07) in comparison with placebo, TNG was not effective in the treatment of colic pain (p<0.05).